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brain aging
A term used in the literature inconjunction with grey matter atrophy, MRI white matter hyperintensity & cardiovascular health.
Management:
- a more favorable cardiovascular health profile* is associated with slower white matter hyperintensity progression
- genetic risk* is associated with faster white matter hyperintensity progression, except if favorable global or behavioral cardiovascular health profile
- genetic risk* is associated with faster grey matter atrophy
* cardiovascular health profile determined by
- 4 behavioral factors: 0 smoking, physical activity, dietary habits, body-mass index
- 3 biological factors:
- total serum cholesterol, blood pressure, fasting plasma glucose from Life's Simple 7
* genetic risk scores determined by the presence of risk alleles for
- hypertension, diabetes, or dyslipidemia
Related
MRI cerebral white matter lesion (white matter hyperintensity)
General
aging
References
- Li Y et al.
Association between behavioral, biological, and genetic markers of cardiovascular
health and MRI markers of brain aging: A cohort study.
Neurology 2022 Nov 1; [e-pub].
PMID: 36319110
https://n.neurology.org/content/100/1/e38