serpin B10; bomapin; peptidase inhibitor 10; PI-10 (SERPINB10, PI10)

Function: - serine protease inhibitor - may play a role in regulation of protease activities during hematopoiesis & apoptosis induced by TNF - may regulate protease activities in the cytoplasm & in the nucleus Structure: - belongs to the serpin family, Ov-serpin subfamily Compartment: nucleus, cytoplasm Expression: - expressed specifically in the bone marrow

General

nuclear protein phosphoprotein serine protease inhibitor; serpin

Properties

SIZE: entity length = 397 aa MW = 45 kD COMPARTMENT: cytoplasm cell nucleus MOTIF: nuclear translocation signal {74-77} Ser phosphorylation site {S307} peptide motif {362-363} INHIBITS: serine protease

Database Correlations

OMIM 602058 UniProt P48595 Pfam PF00079 Entrez Gene 5273 Kegg hsa:5273

References

UniProt :accession P48595