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biogenesis of lysosome-related organelles complex-2 (BLOCK2)

Structure: - consists of: HPS5, HPS6

General

molecular complex

Properties

COMPARTMENT: cell nucleus SUBUNITS: Hermansky-Pudlak syndrome 5 protein COMPARTMENT: cellular membrane MOTIF: alanine-rich region {158-163} MOTIF: alanine residue (SEVERAL) Hermansky-Pudlak syndrome 6 protein COMPARTMENT: cellular membrane MOTIF: glutamate-rich region {34-39} MOTIF: glutamate residue (SEVERAL) consensus repeat {45-51} SEQUENCE-IS: [DE]-X(4)-L-L consensus repeat {147-153} SEQUENCE-IS: [DE]-X(4)-L-L membrane region consensus repeat {516-522} SEQUENCE-IS: [DE]-X(4)-L-L consensus repeat {644-650} SEQUENCE-IS: [DE]-X(4)-L-L peptide motif {698-700}

References

UniProt :accession Q86YV9

Components

Hermansky-Pudlak syndrome 5 protein (alpha-integrin-binding protein 63, Ruby-eye protein 2 homolog, Ru2, HPS5, AIBP63, KIAA1017) Hermansky-Pudlak syndrome 6 protein; Ruby-eye protein homolog; Ru (HPS6)