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Betz cell

Pyramidal neurons in layer 5 of the primary motor cortex One of the largest neurons in the central nervous system Cell bodies may be as large as 100 uM Betz cell send their axons into the spinal cord where they synapse on anterior horn cells Comprise about 10% of pyramidal cells in layer 5b of the primary motor cortex History: - named for Vladimir Alekseyevitch Betz who described these neurons in 1874 Pathology: - target of autoantibody in tropical spastic paraparesis

Related

tropical spastic paraparesis

General

pyramidal cell (neuron)

References

  1. Journal Watch 22(12):95, 2002 Leven MC et al, Nat Med 8:509, 2002 Wurcherpfennig KW, Nat Med 8:455, 2002
  2. Wikepedia, The Free Encyclopedia http://en.wikipedia.org/wiki/Betz_cell
  3. Rivara, CB et al, Stereologic characterization and spatial distribution patterns of Betz cells in the human primary motor cortex. Anat Rec A Discov Mol Cell Evol Biol 2003, 270(2):137 PMID: 12524689