beta-parvin (affixin, PARVB)

Function: 1) role in the regulation of cell adhesion & cytoskeleton organization 2) interacts with integrin-linked protein kinase & actin Structure: - belongs to the parvin family - contains 2 CH domains (calponin-homology domains) Compartment: - cell junction, focal adhesion, cytoplasmic side - constituent of focal adhesions Expression: - expressed predominantly in heart & skeletal muscle

Properties

SIZE: MW = 42 kD entity length = 364 aa COMPARTMENT: cytoplasm MOTIF: calponin homology domain NAME: calponin homology domain SITE: 87-194 calponin homology domain NAME: calponin homology domain SITE: 254-361

Database Correlations

OMIM 608121 UniProt Q9HBI1 Pfam PF00307

References

UniProt :accession Q9HBI1