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beta defensin gene cluster
Contains repeating unit of 7 beta-defensin genes that can occur 1-6 times per haploid genome.
Pathology:
- higher number of gene copies associated with increased risk of psoriasis
Related
beta defensin
General
gene cluster
Properties
LOCUS: human chromosome-8 P
References
- Hollox EJ et al,
Psoriaris is associated with increased beta-defensin genomic
copy number.
Nat Genet 2007,
http://dx.doi.org/1038/ng.2007.48
Components
cytidine
guanosine
thymidine