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betaine-homocysteine S-methyltransferase

Two forms. Function: - role in regulation of homocysteine metabolism - converts betaine to dimethylglycine & & homocysteine to methionine - required for irreversible oxidation of choline - amine & polyamine degradation; betaine degradation sarcosine from betaine: step 1/2 - amino-acid biosynthesis; - L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (BhmT route): step 1/1 trimethylammonioacetate + L-homocysteine = dimethylglycine + L-methionine

Interactions

molecular events

Related

betaine homocysteine

Specific

betaine-homocysteine S-methyltransferase 1 (BHMT) betaine-homocysteine S-methyltransferase 2 (BHMT2)

General

oligomerizing protein S-methyltransferase

Properties

MOTIF: active site

References

  1. UniProt :accession Q93088
  2. UniProt :accession Q9H2M3