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benzoyl peroxide (Panoxyl, Theraderm, Acetoxyl, Asidopan, Persadox, Benoxyl, Lucidol, Mytolac, Oxylite)
Tradename: Panoxyl.
Indications:
- adjunctive treatment of mild to moderate:
a) acne vulgaris
b) acne rosacea
Contraindications:
- pregnancy category: C
Dosage:
1) wash: QD-BID
2) topical: apply sparingly QD initially, the gradually increase to BID-TID PRN
Solution: 2.5%, 4%, 5%, 10%. 1.5 oz.
Adverse effects:
1) many preparations are drying to skin
2) initial facial redness & irritation which resolves with continuous use
3) contact dermatitis
4) dryness & peeling
Mechanism of action:
1) releases active oxygen radicals resulting in a decrease in the number of anaerobic bacteria
2) bactericidal & keratolytic
General
dermatologic agent
peroxide
Properties
Database Correlations
PUBCHEM cid=7187
References
- Saunders Manual of Medical Practice, Rakel (ed),
WB Saunders, Philadelphia, 1996, pg 932
- Drug Information & Medication Formulary, Veterans Affairs,
Central California Health Care System, 1st ed., Ravnan et al
eds, 1998
Component-of
adapalene/benzoyl peroxide (Epiduo)
benzoyl peroxide/clindamycin (BenzaClin)
benzoyl peroxide/clindamycin/phosphate
benzoyl peroxide/cortisol
benzoyl peroxide/doxycycline
benzoyl peroxide/emollient/salicylic acid
benzoyl peroxide/erythromycin (Benzamycin)
benzoyl peroxide/hyaluronate
benzoyl peroxide/hyaluronate based injectable gel
benzoyl peroxide/salicylic acid
benzoyl peroxide/salicylic acid/sulfur
benzoyl peroxide/sulfur
benzoyl peroxide/tretinoin (Benzashave)