benzamidoxime prodrug-converting complex

Function: - reduces N-hydroxylated structures Structure: - subunits: cytochrome b5, NADH-cytochrome b5 reductase (CYB5R3) & MOSC2

General

molecular complex oxidoreductase

Properties

MOTIF: active site SUBUNITS: cytochrome b5 MOTIF: heme-binding site [9-85] MOTIF: Iron [Fe]-binding site SITE: 44-44 Iron [Fe]-binding site SITE: 68-68 transmembrane domain {109-131} cytochrome b5 reductase 3 COMPARTMENT: mitochondria cytoplasm endoplasmic reticulum MOTIF: myristoylation site SITE: N-TERMINUS EFFECTOR-BOUND: myristate Tyr phosphorylation site {Y130} cofactor-binding site [132-162] COFACTOR-BOUND: flavin adenine dinucleotide cofactor-binding site COFACTOR-BOUND: NADH cofactor-binding site [171-206] COFACTOR-BOUND: flavin adenine dinucleotide MOSC domain-containing protein 2, mitochondrial COMPARTMENT: mitochondria MOTIF: MOSC {54-333}

References

UniProt :accession Q8IY31

Components

cytochrome b5 (CYB5A, CYB5) MOSC domain-containing protein 2, mitochondrial (MOSC2, MARC2) NADH cytochrome b5 reductase 3 (B5R, diaphorase-1, CYB5R3, DIA1)