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bcl-2 alpha homodimer
B-cell lymphoma/leukemia-2 dimer alpha splice form. The bcl-2 homodimer may not be the active form of bcl2 [1].
Interactions
molecular events
Related
bcl-2 proto-oncogene
General
anti apoptotic protein
bcl-2 subfamily protein
mitochondrial membrane protein
nuclear protein
oligomerizing protein
proto oncogene protein
Properties
SIZE: MW = 26 kD
entity length = 239 aa
COMPARTMENT: inner mitochondrial membrane
nuclear membrane
endoplasmic reticulum
MOTIF: BH1 domain
NAME: BH1 domain
FOR-BINDING-OF: bax
BH2 domain
NAME: BH2 domain
FOR-BINDING-OF: bax
Database Correlations
OMIM 151430
UniProt P10415
PFAM correlations
Entrez Gene 596
KEGG correlations
References
Korsmeyer TIG 11:101 1995
Component-of
molecular complex