Bcl-2-associated transcription factor 1 (Btf, BCLAF1, KIAA0164)

Function: 1) cell death-promoting transcriptional repressor 2) interacts with Bcl-2 related proteins, EMD, with the Compartment: cytoplasm, nucleus Alternative splicing: named isoforms=4 Expression: ubiquitous

General

phosphoprotein transcriptional silencer (transcriptional repressor)

Properties

SIZE: MW = 106 kD entity length = 920 aa COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S119} serine-rich region {141-148} MOTIF: serine residue (SEVERAL) Ser phosphorylation site {S148} Ser phosphorylation site {S151} Ser phosphorylation site {S153} Ser phosphorylation site {S177} Ser phosphorylation site {S217} Ser phosphorylation site {S222} Ser phosphorylation site {S281} Ser phosphorylation site {S285} Ser phosphorylation site {S290} Ser phosphorylation site {S385} Ser phosphorylation site {S397} Ser phosphorylation site {S496} Ser phosphorylation site {S512} Ser phosphorylation site {S658} serine-rich region {749-763} MOTIF: serine residue (SEVERAL) Ser phosphorylation site {S760} Thr phosphorylation site {T840}

References

UniProt :accession Q9NYF8