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bazedoxifene/conjugated estrogens (Duavee)
bazedoxifene & conjugated equine estrogens
Indications:
- symptomatic treatment of menopause
Dosage:
- conjugated estrogens 0.45 mg plus bazedoxifene 20 mg [2]
Mechanism of action:
- bazedoxifene is a selective estrogen receptor modulator added to inhibit estrogen's endometrial effects [2]
General
pharmacologic combination
References
- Physician's First Watch, Oct. 4, 2013
David G. Fairchild, MD, MPH, Editor-in-Chief
Massachusetts Medical Society
http://www.jwatch.org
- Reuters. Thu Oct 3, 2013 2:47pm EDT
U.S. FDA approves Pfizer drug for menopause symptoms
http://www.reuters.com/article/2013/10/03/us-pfizer-ligand-bazedoxifene-idUSBRE9920WI20131003
- Prescriber's Letter 21(3): 2014
(subscription needed) http://www.prescribersletter.com
Components
bazedoxifene
conjugated estrogens (Premarin, Enjuvia, Cenestin)