bax gene

frameshift mutations found in multiple primary colorectal cancers & cell lines; also T-cell acute lymphoblastic leukemia.

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: BAX-ALPHA messenger RNA TEMPLATE-FOR: BAX-BETA messenger RNA TEMPLATE-FOR: BAX-GAMMA messenger RNA TEMPLATE-FOR: BAX-DELTA SIZE: entity length = 4.5 KB MOTIF: p53-response element (4) transcriptional start site exon (6) intron (5) transcriptional termination site

References

- Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 1993 Aug 27;74(4):609-19. PMID: 8358790