basic helix-loop-helix domain-containing protein KIAA2018 (KIAA2018)

Function: - phosphorylated upon DNA damage, probably by ATM or ATR Structure: contains 1 basic helix-loop-helix (bHLH) domain Compartment: nucleus (putative)

General

nuclear protein phosphoprotein

Properties

SIZE: entity length = 2242 aa MW = 241 kD COMPARTMENT: cell nucleus MOTIF: DNA-binding motif SITE: 17-33 helix-loop-helix NAME: helix-loop-helix SITE: 34-70 FOR-BINDING-VIA: helix-loop-helix coiled coil {77-112} serine-rich region {850-899} MOTIF: serine residue (SEVERAL) glutamine-rich region {1415-1609} MOTIF: glutamine residue (SEVERAL) Ser phosphorylation site {S1769} Ser phosphorylation site {S1775}

Database Correlations

UniProt Q68DE3 Pfam PF00010

References

UniProt :accession Q68DE3