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azilsartan/chlorthalidone (Edarbyclor, Takeda)

Indications: - treatment of hypertension Contraindications: -anuria - not recommended during pregnancy Dosage: - start 40/12.5 mg PO QD - max dosel 40/25 mg PO QD Adverse effects: - most common: dizziness, fatigue - hypokalemia, hyperuricemia - see azilsartan &/or chlorthalidone Mechanism of action: - combines ARB with thiazied diuretic

General

antihypertensive combination

References

  1. Shelly A FDA Approves New Combination for Hypertension Medscape: 12/20/2011 http://www.medscape.com/viewarticle/755844?src=top10

Components

azilsartan (Edarbi) chlorthalidone (Hygroton)