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azelastine (Astelin, Optivar, Azeptin, Azelastinum, Astepro)
Tradename: Astelin (nasal spray)
Tradename: Optivar (ophthalmic agent)
Indications:
- allergic rhinitis (nasal spray)
- allergic conjunctivitis (ophthalmic agent)
- nonallergic vasomotor rhinitis [3]
Dosage:
1) 2 sprays/nostril BID (nasal spray)
- Astepro allegedly tastes better than Astelin
2) 1 drop BID (ophthalmic agent)
Mechanism of action:
1) histamine H1 receptor antagonist
2) mast cell stabilizer
3) decreased chemotaxis of eosinophils
Interactions
drug adverse effects of H1 receptor antagonists
General
H1 receptor antagonist (antihistamine)
mast cell stabilizer
Properties
MISC-INFO: elimination route LIVER
PREGNANCY-CATEGORY -
SAFETY ?
Database Correlations
PUBCHEM correlations
References
- http://www.optivar.com
- Prescriber's Letter 16(3): 2009
New Formulation: Astepro (Azelastine) Nasal Spray
Detail-Document#: 250309
(subscription needed) http://www.prescribersletter.com
- Deprecated Reference
Component-of
azelastine/fluticasone