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axonemal dynein light intermediate polypeptide 1; inner dynein arm light chain, axonemal; hp28 (DNALI1)
Function:
- may play a dynamic role in flagellar motility
Structure:
- belongs to the inner dynein arm light chain family
Expression:
- expressed in many tissues
- smaller 0.9 kb & a larger 2.5 kb transcripts are expressed in testis > prostate, heart, liver, lung & pancreas > ovary, skeletal muscle & small intestine
- not detected in spleen, colon epithelium, thymus or peripheral blood leukocytes
- the 0.9 kb transcript is expressed at a 20-fold higher level than the 2.5 kb transcript in the testis
General
cytoskeletal protein
Properties
SIZE: entity length = 258 aa
MW = 30 kD
COMPARTMENT: cytoplasm
MOTIF: coiled coil {176-255}
Database Correlations
OMIM 602135
UniProt O14645
Pfam PF10211
Entrez Gene 7802
Kegg hsa:7802
References
UniProt :accession O14645