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atrophoderma of Pasini & Pierini
Epidemiology:
- adolescents, young adults
Clinical manifestations:
- single or multiple sharply demarcated, hyperpigmented, nonindurated patches
- usually on the back
- lesions may be discrete or confluent
- patches are marked by a slight depression of the skin, with an abrupt edge
- consistency & feel of the affected skin remains normal [2]
* images [4]
Laboratory:
- none specific
- for exclusion
- thyroid autoantibodies
- anti-thyroid peroxidase Ab
- anti-thyroglobulin Ab
- anti-thyrotropin receptor Ab
- Lyme disease serology (titer)
Management:
- no treatment is consistently effective
- some patients respond to topical corticosteroids, antibiotics, or antimalarials [2]
General
skin disease (dermatologic disorder, dermatopathy, dermatosis)
References
- Wikipedia: Atrophoderma of Pasini and Pierini
http://en.wikipedia.org/wiki/Atrophoderma_of_Pasini_and_Pierini
- Laumann AE and Elston DM
Medscape: eMedicine: Atrophoderma of Pasini and Pierini
http://emedicine.medscape.com/article/1073949-overview
- Lee Y et al
A Case of Atrophoderma of Pasini and Pierini Associated with
Borrelia burgdorferi Infection Successfully Treated with
Oral Doxycycline.
Ann Dermatol. 2011 August; 23(3): 352-356.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162266/
- Handler MZ et al
Congenital idiopathic atrophoderma of Pasini and Pierini
Dermatology Online Journal 18 (4): 4 (2012)
https://escholarship.org/uc/item/8pj8x3bz