ATP-binding cassette, sub-family A (ABC1), member 5

Function: - role in the processing of autolysosomes Structure: - N-glycosylated - belongs to the ABC transporter family, ABCA subfamily - contains 2 ABC transporter domains Compartment: - lysosome membrane - late endosome membrane - Golgi Alternative splicing: named isoforms=3 Expression: - ubiquitously expressed - highly expressed in testis, skeletal muscle, kidney, liver, placenta - expressed in fetal liver, kidney, brain

General

ATP-binding cassette sub-family A (ABC transporter-A, ABCA) glycoprotein transmembrane 15 protein

Properties

SIZE: MW = 187 kD entity length = 1642 aa COMPARTMENT: golgi MOTIF: transmembrane domain {32-52} N-glycosylation site {N86} transmembrane domain {220-240} transmembrane domain {264-284} transmembrane domain {297-317} transmembrane domain {328-348} transmembrane domain {355-375} transmembrane domain {396-416} N-glycosylation site {N458} ABC transporter 1 {478-713} MOTIF: ATP-binding site NAME: ATP-binding site SITE: 514-521 transmembrane domain {866-886} transmembrane domain {967-987} N-glycosylation site {N996} transmembrane domain {1021-1041} transmembrane domain {1071-1091} transmembrane domain {1102-1122} transmembrane domain {1139-1159} transmembrane domain {1169-1189} transmembrane domain {1207-1227} ABC transporter 2 {1290-1533} MOTIF: ATP-binding site NAME: ATP-binding site SITE: 1333-1340

Database Correlations

UniProt Q8WWZ7 Pfam PF00005 Entrez Gene 23461