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asteroid hyalosis

Etiology: - idiopathic - risk factors - diabetes mellitus - hypertension - hypercholesterolemia Pathology: - asteroid bodies are composed of hydroxyapatite associated with lipids suspended within & attached to the hyaluronic acid framework of the vitreous body Clinical manifestations: - multiple small white opacities in the vitreous humor - refractile, often mobile, 'stars in the night sky' - generally unilateral - may obscure view of retina during ophthalmoscopy - generally does not severely affect vision * image & video [3] Differential diagnosis: - vitreous floaters Management: - treatment generally not necessary - vitrectomy

General

eye disease (ophthalmopathy)

References

  1. Wikpedia: Asteroid hyalosis http://en.wikipedia.org/wiki/Asteroid_hyalosis
  2. Kador PF, Wyman M Asteroid hyalosis: pathogenesis and prospects for prevention. Eye (2008) 22, 1278-1285 PMID: 18344964 http://www.nature.com/eye/journal/v22/n10/full/eye200835a.html
  3. Tripathy K Asteroid Hyalosis N Engl J Med 2018; 379:e12. Aug 23, 2018 PMID: 30134134 https://www.nejm.org/doi/full/10.1056/NEJMicm1712355
  4. Handbook of Ocular Disease Management. Asteroid Hylaosis http://cms.revoptom.com/handbook/oct02_sec5_2.htm