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aspirin/codeine (Empirin with Codeine)

DEA-controlled substance: class 3. Contraindications: Avoid use with severe liver disease pregnancy-category D safety in lactation - Dosage: #2: (325 mg aspirin + 15 mg codeine) #3: (325 mg aspirin + 30 mg codeine). #4: (325 mg aspirin + 60 mg codeine) - 1-2 tabs PO every 4 hours. Dosage adjustment with renal failure: creatinine clearance dosage 10-50 mL/min 75% of dose < 10 mL/min avoid use Pharmacokinetics: elimination: liver > kidney

Interactions

drug interactions drug adverse effects of opiates

General

narcotic combination

Database Correlations

PUBCHEM cid=3081774

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Kaiser Permanente Northern California Regional Drug Formulary, 1998

Components

aspirin (Ecotrin, Empirin, Bayer aspirin, Vazalore, ASA) codeine