N-acetylserotonin O-methyltransferase-like protein (ASMTL) gene

Xp22.3; Yp11.3 Structure: - located in the pseudoautosomal region 1 (PAR1) of chromosome X & chromosome Y - represents a unique fusion product of 2 different genes of different evolutionary origin & function - the N-terminus is homologous to the bacterial maf/orfE genes - the C-terminus is homologous to ASMT - exon duplication, exon shuffling & gene fusion seem to be common characteristics of the PAR1 region

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: N-acetylserotonin O-methyltransferase-like protein LOCUS: human Y-chromosome P11 human X-chromosome P22.3 MOTIF: transcription factor binding site transcriptional start site exon intron transcriptional termination site

Database Correlations

OMIM correlations Entrez Gene 8623

References

OMIM :accession 300162