Search
arylalkylamine N-acetyltransferase; pineal serotonin N-acetyltransferase; AA-NAT; serotonin acetylase (AANAT, SNAT)
Function:
1) catalyzes N-acetylation of serotonin into N-acetylserotonin
2) conversion of serotonin to melatonin, penultimate step
Structure:
- monomer (putative)
- belongs to the acetyltransferase family, AANAT subfamily
- contains 1 N-acetyltransferase domain
Expression:
- expressed in pineal gland, retina
Interactions
molecular events
General
acetyltransferase
Properties
SIZE: MW = 23 kD
entity length = 207 aa
MOTIF: N-ACETYLTRANSFERASE {35-194}
MOTIF: tyrosine residue {Y168}
Database Correlations
OMIM 600950
MORBIDMAP 600950
UniProt Q16613
Pfam PF00583
Entrez Gene 15
Kegg hsa:15
ENZYME 2.3.1.87
References
- UniProt :accession Q16613
- SHMPD; The Singapore human mutation and polymorphism database
http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=AANAT
Component-of
molecular complex