Search
aristolochic acid
Component of the Aristolochia genus of plants.
Uses:
- used in Chinese herbal medicines
Adverse effects:
- toxin, mutagen
- renal tubulointerstitial disease
- may be cause of Balkan nephropathy
- increased risk of transitional cell carcinoma [3]
Interactions
drug interactions
drug adverse effects of antihypertensive agents
General
aromatic compound
carboxylate
nitrate
toxin (hazardous material, poison)
Database Correlations
PUBCHEM cid=2236
References
- Hoang ML et al
Mutational signature of aristolochic acid exposure as revealed
by whole-exome sequencing,
Science Translational Medicine, 5: 197ra102, 2013
PMID: 23926200
- Poon SL et al
Genome-wide mutational signatures of aristolochic acid and its
application as a screening tool,
Science Translational Medicine, 5: 197ra101, 2013
PMID: 23926199
- PubChem: 2236
- Medical Knowledge Self Assessment Program (MKSAP) 17,
American College of Physicians, Philadelphia 2015