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AQP7 (aquaporin 7) gene
A segmental duplication of chromosome 9 involving AQP7 is one of the few features distinguishing the human genome from the chimpanzee genome. [1,2]
Related
aquaporin-7; AQP-7; aquaporin adipose; AQPap (AQP7, AQP7L, AQP9)
General
evolutionary divergent human gene
Properties
TEMPLATE-FOR: messenger RNA
TEMPLATE-FOR: aquaporin-7
LOCUS: human chromosome-9 P13
MOTIF: transcription factor binding site
transcriptional start site
exon
intron
transcriptional termination site
Database Correlations
OMIM 602974
Entrez Gene 364
References
- Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L,
Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour-
Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM.
Lineage-specific gene duplication and loss in human and great
ape evolution.
PLoS Biol. 2004 Jul;2(7):E207. Epub 2004 Jul 13.
PMID: 15252450
- Goidts V, Szamalek JM, Hameister H, Kehrer-Sawatzki H.
Segmental duplication associated with the human-specific
inversion of chromosome 18: a further example of the impact of
segmental duplications on karyotype and genome evolution in
primates.
Hum Genet. 2004 Jul;115(2):116-22. Epub 2004 May 7.
PMID: 15133654