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APP C83 peptide fragment
C-terminal peptide fragment generated from the amyloid precursor protein (APP) by APP alpha-secretase. It serves as a substrate for gamma-secretase, but in NOT a precursor of the A4 amyloid peptide (A-beta).
Interactions
molecular events
Related
amyloid precursor protein (APP) or A4/beta amyloid precursor protein
APP alpha-secretase
APP gamma-secretase
General
peptide
Properties
SIZE: entity length = 83 aa
References
- Selkoe DJ.
Alzheimer's disease: genes, proteins, and therapy.
Physiol Rev. 2001 Apr;81(2):741-66. Review.
PMID: 11274343