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apolipoprotein M; apo-M; apoM; protein G3a (APOM, G3A, NG20, HSPC336)

Function: - probably involved in lipid transport - can bind sphingosine-1-phosphate, myristic acid, palmitic acid & stearic acid, retinol, all-trans-retinoic acid & 9-cis-retinoic acid Structure: - belongs to the calycin superfamily, lipocalin family - highly divergent Compartment: - secreted - present in high density lipoprotein (HDL) & to a lesser extent in triglyceride-rich lipoproteins (TGRLP) & low density lipoproteins (LDL) Expression: - expressed in liver & kidney & secreted into plasma

General

apolipoprotein glycoprotein

Properties

SIZE: entity length = 188 aa MW = 21 kD COMPARTMENT: extracellular compartment MOTIF: cysteine residue {C23} MODIFICATION: cysteine residue {C167} cysteine residue {C95} MODIFICATION: cysteine residue {C183} cysteine residue {C128} MODIFICATION: cysteine residue {C157} N-glycosylation site {N135} binding site SITE: 136-136 FOR-BINDING-OF: Fatty acid binding site SITE: 143-143 FOR-BINDING-OF: Fatty acid cysteine residue {C157} MODIFICATION: cysteine residue {C128} cysteine residue {C167} MODIFICATION: cysteine residue {C23} cysteine residue {C183} MODIFICATION: cysteine residue {C95}

Database Correlations

OMIM 606907 UniProt O95445 Pfam PF11032 Entrez Gene 55937 Kegg hsa:55937

References

  1. UniProt :accession O95445
  2. Entrez Gene :accession 55937