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anti-Ma antibody

Etiology: 1) cerebellar degeneration 2) brainstem dysfunction 3) encephalomyelitis 4) multiple associated malignancies Pathology: Neuronal antigen: -> neuronal nuclei & cytoplasm a) Ma1 b) Ma2 c) p40

Related

paraneoplastic antigen Ma1; neuron- & testis-specific protein 1; 37 kD neuronal protein (PNMA1, MA1) paraneoplastic antigen Ma2; onconeuronal antigen Ma2; paraneoplastic neuronal antigen MM2; 40 kD neuronal protein (PNMA2, KIAA0883, MA2)

General

paraneoplastic autoantibody

References

  1. Stuve O & Zamvil SS. In: Medical Immunology 10th edition (2001), Section 3, Clinical Immunology. 38. Neurologic diseases.
  2. Medical Knowledge Self Assessment Program (MKSAP) 15, American College of Physicians, Philadelphia 2009