anti-human globulin test (Coomb's test)

Indications: - evaluation of hemolytic anemia (direct antiglobulin test) Principle: - a test developed by Coomb's in 1945 based upon the principle that specific anti-human immunoglobulins agglutinate erythrocytes coated with human immunoglobulins or complement

Specific

direct antiglobulin test (DAT, direct Coomb's test) indirect antiglobulin test (IAT, indirect Coomb's test)

General

clinical hematology test serology

References

Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 777-780