antibody production

Exposure to antigen results in activation of naive B cells. This activation requires coordination of: 1) dendritic cells (antigen-presenting cells) 2) T-cells 3) B-cells Dendritic cells present antigen to T-cells in the context of of MHC molecules. This activates the T-cells. Antigen is simultaneously processed by B-cells which in turn come into direct contact with activated T-cells. This interaction results in activated B-cells which proliferate & differentiate into 1) plasma cells that secrete antigen-specific antibody 2) memory B-cells

Related

B lymphocyte dendritic cell immunoglobulin memory B lymphocyte plasma cell T lymphocyte (T-cell, thymocyte)

References

Kelly DF et al, Immunological memory: The role of B cells in long-term production against invasive bacterial pathogens. JAMA 2005; 294:3019