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antibiotics & risk of breast cancer
Study observed higher risk of breast cancer in women who had used any antibiotic for > 500 days over 17 years. [1]
- associated with breast cancer at all levels of use [2]
- odds ratio 2.14 for all antibiotics > 500 days of use
- odds ratio 2.26 for macrolide use > 100 days of use
- risk for death with breast cancer even stronger
- maximum odds ratio 5.75
References
- Prescriber's Letter 11(3):16 2004
Detail-Document#: 200310
(subscription needed) http://www.prescribersletter.com
- Journal Watch 24(6):47, 2004
Velicer CM et al
Antibiotic use in relation to the risk of breast cancer.
JAMA 291:827, 2004
PMID: 14970061
- Ness RB & Cauley JA
Antibiotics and breast cancer--what's the meaning of this?
JAMA 291:880, 2004
PMID: 14970068