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ankyrin repeat & IBR domain-containing protein 1 (ANKIB1, KIAA1386)

Function: - E3 ubiquitin-protein ligase (putative) Structure: - belongs to the RBR family - contains 2 ANK repeats - contains 1 IBR-type Zn+2 finger - lacks one Cys in the IBR-type Zn+2 finger domain that is one of the conserved features of the family - contains 2 RING-type Zn+2 fingers - contains 1 UIM (ubiquitin-interacting motif) repeat

Related

IBR domain-containing protein (IBRDC)

General

ankyrin repeat domain protein (ANKRD) myristoylated protein phosphoprotein ring finger protein E3 ubiquitin ligase; ubiquitin-ligating enzyme E3; N end-recognizing protein

Properties

SIZE: entity length = 1089 aa MW = 122 kD COMPARTMENT: cytoplasm MOTIF: myristoylation site SITE: G2 EFFECTOR-BOUND: myristate ankyrin repeat NAME: ankyrin repeat SITE: 45-74 ankyrin repeat NAME: ankyrin repeat SITE: 144-173 RING-finger {333-383} EFFECTOR-BOUND: Zn+2 FOR-BINDING-OF: DNA motif Zinc finger NAME: Zinc finger SITE: 402-478 EFFECTOR-BOUND: Zn+2 RING-finger {519-548} EFFECTOR-BOUND: Zn+2 FOR-BINDING-OF: DNA motif coiled coil {575-640} Ser phosphorylation site {S737} UIM {851-870}

Database Correlations

UniProt Q9P2G1 PFAM correlations Entrez Gene 54467 Kegg hsa:54467

References

UniProt :accession Q9P2G1