angiotensin IV

Function: - role in cognition - role in renal metabolism - role in pathophysiologic conditions - regulation of inflammatory response via NF-kappa-B - binds to receptor LNPEP in brain Structure: - N-terminal angiotensin degradation product Expression: - may be generated from angiotensin-2 during tissue damage

Properties

COMPARTMENT: extracellular compartment

References

- Ruiz-Ortega M et al, The regulation of the inflammatory response through nuclear factor kappaB pathway by angiotensin IV extends the role of the renin angiotensin system in cardiovascular diseases. Trends Cardiovasc Med 2007, 17:19 PMID: 17210474