Search
angiopoietin-related protein 6; angiopoietin-like protein 6; angiopoietin-related growth factor; angiopoietin-related protein 5 (ANGPTL6, AGF, ARP5, UNQ152/PRO178)
Function:
- may play a role in the wound healing process
- may promote epidermal proliferation, remodeling & regeneration
- may promote chemotactic activity of endothelial cells & induce neovascularization
- may counteract high-fat diet-induced obesity & related insulin resistance through increased energy expenditure
Structure:
- contains 1 fibrinogen C-terminal domain
Compartment: secreted (probable)
Related
angiopoietin
General
angiopoietin like
secreted protein
Properties
SIZE: entity length = 470 aa
MW = 52 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-20}
N-glycosylation site {N58}
coiled coil {59-116}
N-glycosylation site {N145}
Fibrinogen C-terminal {251-469}
MOTIF: cysteine residue {C260}
MODIFICATION: cysteine residue {C287}
cysteine residue {C287}
MODIFICATION: cysteine residue {C260}
cysteine residue {C410}
MODIFICATION: cysteine residue {C423}
cysteine residue {C423}
MODIFICATION: cysteine residue {C410}
Database Correlations
OMIM 609336
UniProt Q8NI99
Pfam PF00147
Entrez Gene 83854
Kegg hsa:83854
References
- Entrez Gene :accession 83854
- UniProt :accession Q8NI99