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angiopoietin-related protein 1; angiopoietin-like protein 1; angiopoietin-3; ANG-3 (ANGPTL1, ANG3, ANGPT3, ARP1, PSEC0154, UNQ162/PRO188)
Structure:
- contains 1 fibrinogen C-terminal domain
Compartment: secreted
Expression:
- highly expressed in adrenal gland, placenta, thyroid, heart, skeletal muscle & small intestine
- weakly expressed in testis, ovary, colon, pancreas, kidney & stomach
General
angiopoietin
angiopoietin like
secreted protein
Properties
SIZE: entity length = 491 aa
MW = 57 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-23}
coiled coil {80-168}
MOTIF: N-glycosylation site {N160}
N-glycosylation site {N188}
Fibrinogen C-terminal {271-491}
MOTIF: cysteine residue {C280}
MODIFICATION: cysteine residue {C309}
cysteine residue {C309}
MODIFICATION: cysteine residue {C280}
cysteine residue {C432}
MODIFICATION: cysteine residue {C445}
cysteine residue {C445}
MODIFICATION: cysteine residue {C432}
Database Correlations
OMIM 603874
UniProt O95841
Pfam PF00147
Entrez Gene 9068
Kegg hsa:9068
References
- UniProt :accession O95841
- Entrez Gene :accession 9068