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anetoderma; dermatitis atrophicans maculosa
Classification:
- inflammatory (Jadassohn-Pellizzari)
- noninflammatory (Schweninger-Buzzi)
Etiology:
- primary (idiopathic)
- secondary:
- preceded by an inflammatory or other skin pathology in the same location
- may be associated with systemic disease
- a familial form has been described
Pathology:
- benign condition
- focal loss of dermal elastic tissue
- inflammatory & noninflammatory lesions are histologically similar
Clinical manifestations:
- localized areas of flaccid or herniated saclike skin
- both inflammatory & noninflammatory lesions may be found in the same individual
Laboratory:
- thyroid autoantibodies
- anti-thyroid peroxidase Ab
- anti-thyroglobulin Ab
- anti-thyrotropin receptor Ab
- antiphospholipid antibody
- lupus anticoagulant
- anticardiolipin Ab
- anti beta-2-glycoprotein 1 Ab
- as indicated
- complement C3 in serum, complement C4 in serum
- serology
- antinuclear antibody
- anti-Ro antibody
- anti-La antibody
- antimitochonrial antibody
- anti-smooth muscle antibody
- serum ACE activity
- complete blood count
- erythrocyte sedimentation rate
- Lyme disease serology (titer)
- PPD
- RPR
Management:
- no effective treatment
- surgical excision may be an option if lesions are small & few
General
skin disease (dermatologic disorder, dermatopathy, dermatosis)
References
- Wikipedia: Anetoderma
http://en.wikipedia.org/wiki/Anetoderma
- Laumann AE and Elston DM
Medscape: eMedicine: Anetoderma
http://emedicine.medscape.com/article/1073850-overview