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amoxicillin/clarithromycin/vonoprazan
Indications:
- treatment of Helicobacter pylori infection (FDA approved May 2022)
Adverse effects:
- dysgeusia, diarrhea, abdominal pain, headache, nasopharyngitis, hypertension, vulvovaginal candidiasis
- Stevens-Johnson syndrome & toxic epidermal necrolysis
- C difficile-associated diarrhea
- QT prolongation (clarithromycin)
Notes:
- available Fall 2022
Interactions
drug interactions
General
pharmacologic combination
References
- Hamza Z
Two New Regimens Win FDA Approval for H. Pylori Infection.
Dual and triple vonoprazan-based treatments offer physicians another set of options.
MedPage Today May 4, 2022
https://www.medpagetoday.com/gastroenterology/generalgastroenterology/98547
Components
amoxicillin (Amoxil, Polymox, Larotid, Trimox, DisperMox, Moxatag, A-cillin)
clarithromycin (Biaxin)
vonoprazan (Voquezna)