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Ameloblastin (AMBN)

Function: - role in mineralization & structural organization of enamel Structure: belongs to the ameloblastin family Compartment: - secreted, extracellular space, extracellular matrix Alternative splicing: named isoforms=2 Expression: - meloblast-specific - located at the Tomes, processes of secretory ameloblasts & in the sheath space between rod-interrod enamel

General

matrix protein

Properties

SIZE: entity length = 447 aa MW = 48 kD COMPARTMENT: extracellular matrix MOTIF: signal sequence {1-26} consensus repeat {189-201} consensus repeat {202-214}

Database Correlations

OMIM 601259 UniProt Q9NP70 Pfam PF05111 Entrez Gene 258 Kegg hsa:258

References

UniProt :accession Q9NP70