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alpha-1D adrenergic receptor; alpha 1D-adrenoreceptor; alpha 1D-adrenoceptor; alpha-1A adrenergic receptor; alpha-adrenergic receptor 1a (ADRA1D, ADRA1A)

Function: - alpha-adrenergic receptor - mediates its effect through the influx of extracellular Ca+2 Structure: belongs to the G-protein coupled receptor 1 family Compartment: cell membrane

General

alpha-1 adrenergic receptor glycoprotein

Properties

SIZE: entity length = 572 aa MW = 60 kD COMPARTMENT: synaptic membrane CELL: neuron MOTIF: exoplasmic domain {1-95} MOTIF: N-glycosylation site {N65} N-glycosylation site {N82} transmembrane domain {96-121} cytoplasmic loop {122-133} transmembrane domain {134-159} exoplasmic loop {160-169} transmembrane domain {170-192} cytoplasmic loop {193-213} transmembrane domain {214-238} exoplasmic loop {239-251} transmembrane domain {252-275} cytoplasmic loop {276-348} transmembrane domain {349-373} exoplasmic loop {374-380} transmembrane domain {381-405} cytoplasmic domain {406-572} MOTIF: cysteine residue {C419} MODIFICATION: palmitate COMPARTMENT: membrane arginine-rich region {422-428} MOTIF: arginine residue (SEVERAL)

Database Correlations

OMIM 104219 UniProt P25100 Pfam PF00001 Entrez Gene 146 Kegg hsa:146

References

UniProt :accession P25100