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allergic conjunctivitis; Angelucci's syndrome
see allergic rhinoconjunctivitis
Pathology:
- IgE-mediated mast cell degranulation with release of histamine & other inflmammatory mediators [2]
Clinical manifestations:
- conjunctival erythema
- conjunctival edema
- clear watery discharge (tears) [4]
Management:
- cold compresses [2]
- ophthalmic antihistamines with mast cell-stabilizing properties [2,3]
- alcaftadine, antazoline, azelastine, bepotastine, olopatadine, cetirizine ...
- oral antihistamines
- artificial tears
Related
allergic rhinitis (hay fever, ragwood allergy)
Specific
allergic rhinoconjunctivitis (hayfever)
General
type 1 hypersensitivity; immediate hypersensitivity (allergy)
conjunctivitis
References
- Prescriber's Letter 14(1): 2007
Ophthalmic Medications for Allergic Conjunctivitis
Detail-Document#: 230106
(subscription needed) http://www.prescribersletter.com
- Medical Knowledge Self Assessment Program (MKSAP) 16, 19
American College of Physicians, Philadelphia 2012, 2022
- Bielory L, Delgado L, Katelaris CH, et al.
ICON: diagnosis and management of allergic conjunctivitis.
Ann Allergy Asthma Immunol. 2020;124:118-34.
PMID: 31759180
- NEJM Knowledge+
- Bilkhu PS, Wolffsohn JS, Naroo SA, Robertson L, Kennedy R.
Effectiveness of nonpharmacologic treatments for acute seasonal allergic
conjunctivitis.
Ophthalmology. 2014 Jan;121(1):72-78.
PMID: 24070810 Clinical Trial.