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alkaline ceramidase 2 (AlkCDase 2, acylsphingosine deacylase 3-like, N-acylsphingosine amidohydrolase 3-like, ASAH3L, ACER2, PP11646)
Function:
- hydrolyzes sphingolipid ceramide into sphingosine & free fatty acid
N-acylsphingosine + H2O a carboxylate + sphingosine
Structure: belongs to the alkaline ceramidase family
Compartment: Golgi membrane
Alternative splicing: named isoforms=3
General
ceramidase
glycoprotein
transmembrane 7 protein
Properties
SIZE: MW = 31 kD
entity length = 275 aa
COMPARTMENT: golgi
MOTIF: N-glycosylation site {N23}
transmembrane domain {33-53}
transmembrane domain {63-83}
transmembrane domain {87-107}
transmembrane domain {125-142}
transmembrane domain {144-164}
transmembrane domain {174-194}
transmembrane domain {212-232}
Database Correlations
UniProt Q5QJU3
Pfam PF05875
ENZYME 3.5.1.23
References
UniProt :accession Q5QJU3