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Aldurazyme (alpha-L-iduronidase)

Tradename: Aldurazyme (FDA approved 2003) Indications: -> mucopolysaccharidosis 1 (Hurler-Scheie syndrome) Mechanism of action: - enzyme replacement therapy - hydrolysis of unsulfated alpha-L-iduronosidic linkages in dermatan sulfate

General

alpha-L-iduronidase (laronidase, Aldurazyme, IDUA) metabolic agent (metabolic modifier)

References

  1. UniProt :accession P35475
  2. Prescriber's Letter 11(2):suppl 2004