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aldo-keto reductase family 1 member C-like protein 2; testis-specific protein HTSP; LoopADR (AKR1CL2, AKRDC1, AKR1E2)
Function:
- testis-specific oxidoreductase
Kinetic parameters:
- KM=6.1 uM for 9,10-phenanthrenequinone with NADPH as cofactor
- Vmax=0.42 nmol/min/mg enzyme towards 9,10-phenanthrenequinone with NADPH as cofactor
Structure: belongs to the aldo/keto reductase family
Compartment: cytoplasm
Alternative splicing: named isoforms=5
Expression: testis-specific
General
oxidoreductase
phosphoprotein
testis-specific protein
Properties
SIZE: MW = 37 kD
entity length = 320 aa
COMPARTMENT: cytoplasm
MOTIF: tyrosine residue {Y40}
Lowers pKa of active site Tyr {69-69}
binding site
SITE: 102-102
FOR-BINDING-OF: Substrate
Database Correlations
UniProt Q96JD6
Pfam PF00248
References
UniProt :accession Q96JD6