Search
aldosterone in 24 hour urine
Reference interval:
- 5-19 ug/24 hours (13.9-52.7 nmol/24 hours)*
* 24 hour urine, assumes normal sodium intake
* cutoff for diagnosis of primary hyperaldosteronism is 12 ug/24 hours [3]
Increases:
- primary hyperaldosteronism
- angiotensin
- corticotropin
- ethacrynic acid
- lithium carbonate
- loop diuretics: furosemide
- thiazide diuretics
- oral contraceptives (some)
Decreases:
- aminoglutethimide
- clonidine
- deoxycorticosterone
- fludrocortisone
- glucocorticoids
- labetalol
- licorice
- heparin
- metyrapone
- propranol
Methods:
- see aldosterone in serum/urine
Specimen:
- urine 4 hours, refrigerate during collection
a) add 50% acetic acid at completion of collection to adjust pH to 2-4
b) store frozen
Related
renin-angiotensin-aldosterone axis
Specific
aldosterone free in 24 hour urine
General
aldosterone in urine
24 hour urine
References
- Clinical Guide to Laboratory Tests, 3rd edition, NW Tietz
ed, WB Saunders, Philadelphia, 1995
- Panel of 6 tests
Laboratory Test Directory ARUP: 70480
- Brown JM, Siddiqui M, Calhoun DA et al.
The unrecognized prevalence of primary aldosteronism:
A cross-sectional study.
Ann Intern Med 2020 May 26; [e-pub].
PMID: 32449886
https://www.acpjournals.org/doi/10.7326/M20-0065
- Funder JW.
Primary aldosteronism: At the tipping point.
Ann Intern Med 2020 May 26; [e-pub].
PMID: 32449882
https://www.acpjournals.org/doi/10.7326/M20-1758
Component-of
oral salt loading test
salt loading test