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neuroblast differentiation-associated protein AHNAK; desmoyokin (AHNAK, PM227)
Function:
- may be required for neuronal cell differentiation
- interacts with DYSF (Ca+2-independent)
Structure:
- contains 1 PDZ domain (DHR domain)
Compartment:
- nucleus
General
nuclear protein
phosphoprotein
Properties
SIZE: entity length = 5890 aa
MW = 629 kD
COMPARTMENT: cell nucleus
MOTIF: PDZ domain
NAME: PDZ domain
SITE: 9-90
MOTIF: Ser phosphorylation site {S41}
Ser phosphorylation site {S93}
Ser phosphorylation site {S177}
Ser phosphorylation site {S210}
Ser phosphorylation site {S216}
Thr phosphorylation site {T490}
Ser phosphorylation site {S511}
Ser phosphorylation site {S559}
Ser phosphorylation site {S570}
Tyr phosphorylation site {Y715}
Ser phosphorylation site {S793}
Tyr phosphorylation site {Y836}
Tyr phosphorylation site {Y964}
Ser phosphorylation site {S1068}
Tyr phosphorylation site {Y1469}
Ser phosphorylation site {S2397}
Thr phosphorylation site {T3716}
Ser phosphorylation site {S4684}
Thr phosphorylation site {T4766}
Ser phosphorylation site {S4812}
Ser phosphorylation site {S4903}
Ser phosphorylation site {S4960}
nuclear translocation signal {4971-4979}
Ser phosphorylation site {S4986}
Ser phosphorylation site {S4993}
Thr phosphorylation site {T5009}
nuclear translocation signal {5019-5027}
nuclear translocation signal {5034-5039}
Ser phosphorylation site {S5077}
Tyr phosphorylation site {Y5089}
Ser phosphorylation site {S5099}
Ser phosphorylation site {S5110}
Ser phosphorylation site {S5332}
Ser phosphorylation site {S5397}
Thr phosphorylation site {T5415}
Ser phosphorylation site {S5448}
glycine-rich region {5458-5654}
MOTIF: Ser phosphorylation site {S5552}
Ser phosphorylation site {S5555}
Ser phosphorylation site {S5620}
nuclear translocation signal {5706-5716}
Ser phosphorylation site {S5731}
Ser phosphorylation site {S5739}
Ser phosphorylation site {S5749}
Ser phosphorylation site {S5752}
Ser phosphorylation site {S5763}
Ser phosphorylation site {S5769}
nuclear translocation signal {5772-5779}
Ser phosphorylation site {S5780}
Ser phosphorylation site {S5782}
Ser phosphorylation site {S5784}
Ser phosphorylation site {S5793}
Thr phosphorylation site {T5794}
Ser phosphorylation site {S5830}
Tyr phosphorylation site {Y5836}
Ser phosphorylation site {S5841}
Ser phosphorylation site {S5851}
Ser phosphorylation site {S5854}
Ser phosphorylation site {S5857}
Database Correlations
OMIM 103390
UniProt Q09666
Pfam PF00595
Entrez Gene 79026
Kegg hsa:79026
References
UniProt :accession Q09666