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age-associated changes in the skeletal system
The skeletal system undergoes change with aging.
Physiology:
1) decreased osteoclast bone formation
2) osteoporosis
a) both trabecular bone & cortical bone affected
b) women > men
c) slower healing of fractures
3) disorder of cartilage matrix
- loss of fluid from intervertebral discs resulting in shortening of the spine, kyphosis [5]
- joints become stiffer & less flexible
4) modified proteoglycans & glycosaminoglycans
5) osteoarthritis
Related
bone disease; osteopathia
orthopedic disorders in the elderly
skeleton (skeletal system)
General
age-related physiological changes
References
- Essentials of Clinical Geriatrics, 4th ed, Kane RL et al (eds)
McGraw Hill, NY, 1999
- UCLA Intensive Course in Geriatric Medicine & Board
Review, Marina Del Ray, CA, Sept 29-Oct 2, 2004
- The Merck Manual of Geriatrics, 3rdh ed, Merck & Co,
Rahway NJ, 2000
- Taffet GE, Physiology of Aging,
In: Geriatric Medicine: An Evidence-Based Approach, 4th ed,
Cassel CK et al (eds), Springer-Verlag, New York, 2003
- Geriatric Review Syllabus, 8th edition (GRS8)
Durso SC and Sullivan GN (eds)
American Geriatrics Society, 2013