Search
ETS translocation variant 4; adenovirus E1A enhancer-binding protein; E1A-F (ETV4, E1AF)
Function:
- transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'
Structure:
- belongs to the ETS family
- contains 1 ETS DNA-binding domain
Compartment: nucleus
General
DNA-binding protein
phosphoprotein
Properties
SIZE: entity length = 484 aa
MW = 54 kD
COMPARTMENT: cell nucleus
MOTIF: acidic region {49-75}
MOTIF: acidic residue (SEVERAL)
Ser phosphorylation site {S140}
glutamine-rich region {148-244}
MOTIF: glutamine residue (SEVERAL)
Ser phosphorylation site {S149}
ETS domain
NAME: ETS domain
SITE: 341-421
Database Correlations
OMIM 600711
UniProt P43268
PFAM correlations
Entrez Gene 2118
Kegg hsa:2118
References
UniProt :accession P43268