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adenosylhomocysteinase 3; S-adenosyl-L-homocysteine hydrolase 3; AdoHcyase 3 (AHCYL2, KIAA0828)
Function:
- amino-acid biosynthesis, homocysteine biosynthesis L-homocysteine from S-adenosyl-L-homocysteine, step 1/1
- activated methyl cycle
S-adenosyl-L-homocysteine + H2O L-homocysteine + adenosine
Cofactor: binds 1 NAD per subunit
Structure: belongs to the adenosylhomocysteinase family
Related
adenosylhomocysteinase 2; AdoHcyase 2; DC-expressed AHCY-like molecule; S-adenosyl-L-homocysteine hydrolase 2; S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1, DCAL, XPVKONA)
S-adenosyl homocysteine hydrolase (ADOHCYASE, adenosylhomocysteinase, AHCY, SAHH)
General
hydrolase
phosphoprotein
Properties
SIZE: MW = 67 kD
entity length = 611 aa
MOTIF: Ser phosphorylation site {S107}
binding site
SITE: 236-236
FOR-BINDING-OF: Substrate
binding site
SITE: 310-310
FOR-BINDING-OF: Substrate
binding site
SITE: 335-335
FOR-BINDING-OF: Substrate
NAD binding {362-529}
MOTIF: binding site
SITE: 365-365
FOR-BINDING-OF: Substrate
binding site
SITE: 369-369
FOR-BINDING-OF: Substrate
Database Correlations
UniProt Q96HN2
PFAM correlations
ENZYME 3.3.1.1
References
UniProt :accession Q96HN2