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acyl-protein thioesterase 2 (lysophospholipase 2, LPL-I, LYPLA2)
Function:
- may hydrolyze fatty acids from S-acylated Cys in proteins such as trimeric G alpha proteins or HRAS
- as lysophospholipase activity
palmitoyl-protein + H2O palmitate + protein
Structure: belongs to the AB hydrolase 2 family
Compartment: cytoplasm
General
lysophospholipase
thiol esterase or thioesterase
Properties
SIZE: MW = 25 kD
entity length = 231 aa
COMPARTMENT: cytoplasm
MOTIF: serine residue {S122}
aspartate residue {D176}
histidine residue {H210}
Database Correlations
UniProt O95372
Pfam PF02230
References
UniProt :accession O95372