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mediator of RNA polymerase II transcription subunit 4; activator-recruited cofactor 36 kD component; ARC36; mediator complex subunit 4; TRAP/SMCC/PC2 subunit p36 subunit; vitamin D3 receptor-interacting protein complex 36 kD component; DRIP36 (MED4, ARC36, DRIP36, VDRIP, HSPC126)

Function: - component of the mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase 2- dependent genes Structure: -belongs to the mediator complex subunit 4 family Compartment: nucleus

General

phosphoprotein transcription factor (TF)

Properties

SIZE: entity length = 270 aa MW = 30 kD COMPARTMENT: cell nucleus MOTIF: coiled coil {24-48} MOTIF: Ser phosphorylation site {S32} coiled coil {90-131} serine-rich region {262-269} MOTIF: serine residue (SEVERAL)

Database Correlations

OMIM 605718 UniProt Q9NPJ6 Pfam PF10018 Entrez Gene 29079 Kegg hsa:29079

References

UniProt :accession Q9NPJ6

Component-of

mediator complex (mediator of RNA polymerase 2 transcription)