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mediator of RNA polymerase II transcription subunit 4; activator-recruited cofactor 36 kD component; ARC36; mediator complex subunit 4; TRAP/SMCC/PC2 subunit p36 subunit; vitamin D3 receptor-interacting protein complex 36 kD component; DRIP36 (MED4, ARC36, DRIP36, VDRIP, HSPC126)
Function:
- component of the mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase 2- dependent genes
Structure: -belongs to the mediator complex subunit 4 family
Compartment: nucleus
General
phosphoprotein
transcription factor (TF)
Properties
SIZE: entity length = 270 aa
MW = 30 kD
COMPARTMENT: cell nucleus
MOTIF: coiled coil {24-48}
MOTIF: Ser phosphorylation site {S32}
coiled coil {90-131}
serine-rich region {262-269}
MOTIF: serine residue (SEVERAL)
Database Correlations
OMIM 605718
UniProt Q9NPJ6
Pfam PF10018
Entrez Gene 29079
Kegg hsa:29079
References
UniProt :accession Q9NPJ6
Component-of
mediator complex (mediator of RNA polymerase 2 transcription)